Seroatlas · Human Serome Atlas

FRMPD2B

Putative protein FRMPD2-like

Also known as: FRP2L_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q6IN97
Gene: FRMPD2B
Canonical length: 320 aa

OverviewNCBI Gene

No narrative summary is available for FRMPD2B in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

320 residues, UniProt reviewed canonical sequence.

>Q6IN97|FRMPD2B
     1  MTSIPFPGDR LLQVDGVILC GLTHKQAVQC LKGPGQVARL VLERRVPRST QQCPSANDSM
    61  GDERTAVSLV TALPGRPSSC VSVTDGPKFE VKLKKNANGL GFSFVQMEKE SCSHLKSDLV
   121  RIKRLFPGQP AEENGAIAAG DIILAVNGRS TEGLIFQEVL HLLRGAPQEV TLLLCRPPPG
   181  ALPEMEQEWQ TPELSADKEF TRATCTDSCT SPILDQEDSW RDSASPDAGE GLGLRPESSQ
   241  KAIREAQWGQ NRERPWASSL THSPESHPHL CKLHQERDES TLATSLEKDV RQNCYSVCDI
   301  MRLGRYSFSS PLTRLSTDIF

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against FRMPD2B can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.54

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Repeat

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads FRMPD2B as an antibody target. Whether an autoantibody or antibody against FRMPD2B could matter depends on whether native FRMPD2B is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

FRMPD2B is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label FRMPD2B as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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