Seroatlas · Human Serome Atlas

FRMD6-AS1

Putative uncharacterized protein FRMD6-AS1

Also known as: FMAS1_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
P0C7T7
Gene
FRMD6-AS1
Canonical length
363 aa

OverviewNCBI Gene

No narrative summary is available for FRMD6-AS1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

363 residues, UniProt reviewed canonical sequence.

>P0C7T7|FRMD6-AS1
     1  MQLGRSGRRS QKQKHEVDEV YFTLTRVDRS CPYLTVPGPP GAESGAPVRL GLRQRAVSSS
    61  RNPNSAGRTP NSYLTQAPVW RRSAPAQPPA PQTRHFPGRG ADPALGSLPA AGLSGLCART
   121  TGGTAQPPGA RDSGASPGAQ PQRHRPGCRG PPGSPVIRGP PRCREPGTAH GAQTPPPTRP
   181  NWPRRQPSRG SCALSSRQYG ERPPAPPWTQ PSVPRRGAAT WGQEKAEYAT PLGTQEARRA
   241  SGGRGGVDHG DQGLSPCCGD GGARGRRRLP TFWPSGLLRL RLDSLGALPP EPSRAGRGRL
   301  FGLSVVLLKR NAGGEATPRE GGPRRRWLRE SCSPLPARHS RRRASWVSRW MEGAPPRMPS
   361  LPL

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against FRMD6-AS1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.74

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads FRMD6-AS1 as an antibody target. Whether an autoantibody or antibody against FRMD6-AS1 could matter depends on whether native FRMD6-AS1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

FRMD6-AS1 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label FRMD6-AS1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/FRMD6-AS1. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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