Seroatlas · Human Serome Atlas

FP248

Putative chemokine-related protein FP248

Also known as: YH006_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q71RG6
Gene: FP248
Canonical length: 208 aa

OverviewNCBI Gene

No narrative summary is available for FP248 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

208 residues, UniProt reviewed canonical sequence.

>Q71RG6|FP248
     1  MGTGGSLLCG CSLVLSCLCP SASLPDPGNS TWPPGAQAGL PAALALPLPR LPRILFPMAG
    61  RPARPSSDFV GCAQGMCCHG RQGTVHIHTS SVSCWTPCPV TGTGGTAVSR KDRVLPHRRQ
   121  VSLACVCAVG ERAGQLWSQK PVQMARPSAR HLLPRGSSPN SQAVLLPSVC PVPWPPVGPS
   181  PGQGEGLSPA FPGVGTDRGD SWALVLQV

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against FP248 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Secreted
Secreted: Yes
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.68

OntologyGO

Cellular components

extracellular region

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads FP248 as an antibody target. Whether an autoantibody or antibody against FP248 could matter depends on whether native FP248 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

FP248 is annotated as secreted, so native FP248 circulates and is directly accessible to antibodies. Secreted and cell-surface proteins are the autoantibody targets most likely to act like drugs, blocking or depleting the native protein.

Annotation status

The present source text does not explicitly label FP248 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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