Seroatlas · Human Serome Atlas

FER1L6-AS2

Putative uncharacterized protein encoded by FER1L6-AS2

Also known as: FEAS2_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
Q96M78
Gene
FER1L6-AS2
Canonical length
137 aa

OverviewNCBI Gene

No narrative summary is available for FER1L6-AS2 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

137 residues, UniProt reviewed canonical sequence.

>Q96M78|FER1L6-AS2
     1  MSQVGRVRSS HHFESVCLDA EVRVVLVALD HAGLHTLSSA LNESLRPIHR EELHLLHFPN
    61  SPEENLRKRP AEPSPQIHGG APHLPWLCVE KLDLLPENHA VFLQERTAQL FEGSFFFSRS
   121  PAHSISPLLQ FRWGHCP

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against FER1L6-AS2 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.42

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads FER1L6-AS2 as an antibody target. Whether an autoantibody or antibody against FER1L6-AS2 could matter depends on whether native FER1L6-AS2 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

FER1L6-AS2 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label FER1L6-AS2 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/FER1L6-AS2. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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