Seroatlas · Human Serome Atlas

FAM90A27P

Protein FAM90A27P

Also known as: F90AR_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
A6NNH2
Gene
FAM90A27P
Canonical length
459 aa
Protein class
Predicted intracellular proteins

OverviewNCBI Gene

No narrative summary is available for FAM90A27P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

459 residues, UniProt reviewed canonical sequence.

>A6NNH2|FAM90A27P
     1  MARHSVHHQA QRPPRAKNPQ EQQRRPMGQT TLPAEQEESR VKCKNCGAFG HSARSKTCPI
    61  KRWSGALPLQ ALGSHKEKEN LKPAKAQLPF TTPGPFTTND REKERSPSPQ QQQSEAPTQT
   121  FPRTPQEKMQ EAWKEPAEDC LFLRHPTMPL PVHTTKKRSV LGPVSTGPPP VNKPEMRLLC
   181  PSGHNDSPQL STCGPTKGHG RDVTASLLPV LKSSHQTPTL SARLPANRPD MSSHGALQPA
   241  MQALALGPGL KSQAEIKHPD ADAKPRPQQV RKQCGQDSRT QAPDKEPAPV PTQTFQNPAK
   301  KARFSSFQTP ALRTQLPDVG AVQTLQPPRT ATGLGSKEAP KATAETAATK TATLQPRVNL
   361  QPAPSSPFLG PAQGCPVLQP GPPIHVPGRP GSVTFMRGDK GQKSPRFRMP PTSRPPENSA
   421  SAQSPRFSRQ PEGQGPQVST SVLYEDLLVT SSSEDSDSD

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against FAM90A27P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.72
Highest tissue expression
0.2 nTPM

Expression across tissuesHPA

Tissue

  • testis: 0.2 nTPM
  • adipose tissue: 0 nTPM
  • adrenal gland: 0 nTPM
  • appendix: 0 nTPM
  • bone marrow: 0 nTPM
  • breast: 0 nTPM

Single-cell type

  • early spermatids: 1.5 nCPM
  • late spermatids: 0.7 nCPM
  • monocyte progenitors: 0.2 nCPM
  • pituitary stem cells: 0.2 nCPM
  • decidual stromal cells: 0.1 nCPM
  • differentiating spermatogonia: 0.1 nCPM

Immune cell

  • basophil: 0 nTPM
  • classical monocyte: 0 nTPM
  • eosinophil: 0 nTPM
  • gdT-cell: 0 nTPM
  • intermediate monocyte: 0 nTPM
  • MAIT T-cell: 0 nTPM

Brain region

  • amygdala: 0 nTPM
  • basal ganglia: 0 nTPM
  • cerebellum: 0 nTPM
  • cerebral cortex: 0 nTPM
  • choroid plexus: 0 nTPM
  • hippocampal formation: 0 nTPM

Protein domainsUniProt · Pfam · InterPro

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads FAM90A27P as an antibody target. Whether an autoantibody or antibody against FAM90A27P could matter depends on whether native FAM90A27P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

FAM90A27P is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label FAM90A27P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/FAM90A27P. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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