FAM86JP
Putative protein FAM86JP
Also known as: F86JP_HUMAN
Protein identityUniProt · HPA
OverviewNCBI Gene
No narrative summary is available for FAM86JP in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
40 residues, UniProt reviewed canonical sequence.
>Q05BU3|FAM86JP
1 MPGAFSQNSS KRRAVLPRSH RVAGRGPAEA GCLPGAPAGSLocalizationUniProt · AlphaFold · HPA
Whether an antibody against FAM86JP can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Unknown
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.72
Cancer expressionTCGA
Across TCGA tumor cohorts, this protein is over-expressed in roughly 8% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads FAM86JP as an antibody target. Whether an autoantibody or antibody against FAM86JP could matter depends on whether native FAM86JP is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
FAM86JP is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label FAM86JP as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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