Seroatlas · Human Serome Atlas

FAM86C2P

Putative protein FAM86C2P

Also known as: F86C2_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A6NEL3
Gene: FAM86C2P
Canonical length: 165 aa

OverviewNCBI Gene

No narrative summary is available for FAM86C2P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

165 residues, UniProt reviewed canonical sequence.

>A6NEL3|FAM86C2P
     1  MAPEENAGTE LLLQSLERRF LAARALRSFP WQSLEAKLRD SSDSELLRDI LQKHEAVHTE
    61  PLDELYEVLA ETLMAKESTQ GHRSYLLTCC IAQKPSCRWS GSCGGWLPAG STSGLLKSMW
   121  PLPSATQRRA SCSPLSYAGL GSDGKWNLVM TRNCFPTKST WRWQC

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against FAM86C2P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.51

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 6% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

OntologyGO

Biological processes

methylation

Molecular functions

methyltransferase activity

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads FAM86C2P as an antibody target. Whether an autoantibody or antibody against FAM86C2P could matter depends on whether native FAM86C2P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

FAM86C2P is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label FAM86C2P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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