Seroatlas · Human Serome Atlas

FAM47DP

Putative protein FAM47D

Also known as: FA47D_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
A6NHR8
Gene
FAM47DP
Canonical length
397 aa

OverviewNCBI Gene

No narrative summary is available for FAM47DP in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

397 residues, UniProt reviewed canonical sequence.

>A6NHR8|FAM47DP
     1  MGDQRPRDRP RSPGMDCKPW YCDKPPSKYI AKRKHRRLRF PPMDTQNWVF VKESMDSFHY
    61  GCPSPEDMLI CRLNEFLLPK ISHRGPQADP KSRQKKLLKK VALFSKLLPA QPAWKAFVEE
   121  AQLMAKHPLA MYPNLGEDMP PDLLLQMLKL LDPERKLEKA WAYCEGREKT IKEPTKPEPP
   181  KAPVSHHFLE PPKIRASCLK ELLQEDTPST TECVSDSLQH RYTSRKMHDF KWARDMGVDE
   241  ESIRNLFDFT PKWRATYEDQ QIKKIKEWVS ELQYRIKLDE MDEVESSQEK DWDRKLQMAP
   301  NSYTAQCVKM RYGVWYLKPK LGKKLRSDQP LIDPKLLLEK PDEPDILDDL YGPIAFKDFI
   361  LSKGYEMPGI IERLCARKGW TYDSVKTPVQ RAMRLYK

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against FAM47DP can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.59

Protein domainsUniProt · Pfam · InterPro

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads FAM47DP as an antibody target. Whether an autoantibody or antibody against FAM47DP could matter depends on whether native FAM47DP is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

FAM47DP is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label FAM47DP as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/FAM47DP. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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