Seroatlas · Human Serome Atlas

FAM30A

Putative uncharacterized protein FAM30A

Also known as: FA30A_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
Q9NZY2
Gene
FAM30A
Canonical length
134 aa

OverviewNCBI Gene

No narrative summary is available for FAM30A in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

134 residues, UniProt reviewed canonical sequence.

>Q9NZY2|FAM30A
     1  MGTLQGAALR SRERPSWPQE THGHRERTEE GCAVAAFSAD ALRTGGQELE QTGLRPKAGA
    61  PPMPDLLGHR ICTDIGKGWR MDGGRTCSCS SFCRCPERGA RRSSPDAPGL ALDFPLLLDL
   121  LWHLCSWTSQ PLEL

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against FAM30A can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.66

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 2% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads FAM30A as an antibody target. Whether an autoantibody or antibody against FAM30A could matter depends on whether native FAM30A is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

FAM30A is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label FAM30A as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/FAM30A. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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