FAM201A
Protein FAM201A
Also known as: F201A_HUMAN
Protein identityUniProt · HPA
OverviewNCBI Gene
No narrative summary is available for FAM201A in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
155 residues, UniProt reviewed canonical sequence.
>Q5SY85|FAM201A
1 MGLRAGSRCR ADHLAQPQPQ GHLAPVLRCG ECWRARGLPG GCCLHTEGGC SLGAQAGWRT
61 AGWEARGRRD LGLETTSAHS RSLLHLSSWR RPDVGEAAGA ELLQRAPLQQ PDPAQAAVEG
121 GLLARLPRPQ DQGCGQHRPH SPRLVDIALP GGGWTLocalizationUniProt · AlphaFold · HPA
Whether an antibody against FAM201A can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Unknown
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.7
Cancer expressionTCGA
Across TCGA tumor cohorts, this protein is over-expressed in roughly 4% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads FAM201A as an antibody target. Whether an autoantibody or antibody against FAM201A could matter depends on whether native FAM201A is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
FAM201A is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label FAM201A as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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