Seroatlas · Human Serome Atlas

FAM120A2P

Putative uncharacterized protein FAM120A2P

Also known as: CI129_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q5T035
Gene: FAM120A2P
Canonical length: 196 aa

OverviewNCBI Gene

No narrative summary is available for FAM120A2P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

196 residues, UniProt reviewed canonical sequence.

>Q5T035|FAM120A2P
     1  MPGMVPPHVP PQMLNIPQTS LQAKPVAPQV PSPGGAPGQG PYPYSLSEPA PLTLDTSGKN
    61  LTEQNSYSNI PHEGKHTPLY ERSLPINPAQ SGSPNHVDSA YFPGSSTSSS SDNDEGSGGA
   121  TKYTIYWGFR ATDHHVQGRD SQARGTAAHW HGGHVCSPNV FWRISHGPAQ QLTFPTEQAA
   181  PPVCPAPASR RLSAPG

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against FAM120A2P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.69

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 3% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads FAM120A2P as an antibody target. Whether an autoantibody or antibody against FAM120A2P could matter depends on whether native FAM120A2P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

FAM120A2P is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label FAM120A2P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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