Seroatlas · Human Serome Atlas

ERC2-IT1

Putative uncharacterized protein encoded by ERC2-IT1

Also known as: ERIT1_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: O76042
Gene: ERC2-IT1
Canonical length: 136 aa

OverviewNCBI Gene

No narrative summary is available for ERC2-IT1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

136 residues, UniProt reviewed canonical sequence.

>O76042|ERC2-IT1
     1  MLACFPCFLR RKMPCLLKVA DAGCSVGLGK VHCSCHLPNP RVLRHCDILT GVLTLGLDMS
    61  CHACLSAGTG LGEELVGLGP GSTCLVKHLW LLFPCHRLAS QNYSDSLAQQ WSFSLLIMWL
   121  CNREREIFMS KCAKCI

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against ERC2-IT1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.45

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads ERC2-IT1 as an antibody target. Whether an autoantibody or antibody against ERC2-IT1 could matter depends on whether native ERC2-IT1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

ERC2-IT1 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label ERC2-IT1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Loading the interactive Seroatlas protein explorer...