Seroatlas · Human Serome Atlas

EEF1DP3

Putative elongation factor 1-delta-like protein

Also known as: EF1DL_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q658K8
Gene: EEF1DP3
Canonical length: 133 aa

OverviewNCBI Gene

No narrative summary is available for EEF1DP3 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

133 residues, UniProt reviewed canonical sequence.

>Q658K8|EEF1DP3
     1  MATNFLVGEK IWFHKFKYGD AERRFYEQMN GPVAGASLQE ASMILHDIAR ARENIPKSLA
    61  GSLGPGASSG PSGDHSELVV RIASLEVDNQ RDLAERAGEE LARPLGHSPA DPAHVSHAPS
   121  GAPGQEASHT SRG

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against EEF1DP3 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.58

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 4% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

OntologyGO

Molecular functions

translation elongation factor activity

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads EEF1DP3 as an antibody target. Whether an autoantibody or antibody against EEF1DP3 could matter depends on whether native EEF1DP3 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

EEF1DP3 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label EEF1DP3 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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