Seroatlas · Human Serome Atlas

DPH3P1

Putative DPH3 homolog B

Also known as: DPH3B_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q9H4G8
Gene: DPH3P1
Canonical length: 78 aa

OverviewNCBI Gene

No narrative summary is available for DPH3P1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

78 residues, UniProt reviewed canonical sequence.

>Q9H4G8|DPH3P1
     1  MAVFHDEVEI EDFQYDEDSE TYFCPCPCGD NFSITKEELE NGEGVAMCPG CSLIIKVIYD
    61  KDQFACGETV PVPSVNKE

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against DPH3P1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.41

OntologyGO

Biological processes

protein histidyl modification to diphthamide

Molecular functions

metal ion binding

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads DPH3P1 as an antibody target. Whether an autoantibody or antibody against DPH3P1 could matter depends on whether native DPH3P1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

DPH3P1 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label DPH3P1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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