Seroatlas · Human Serome Atlas

DNM1P34

Putative GED domain-containing protein DNM1P34

Also known as: DMP34_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q6PK57
Gene: DNM1P34
Canonical length: 102 aa

OverviewNCBI Gene

No narrative summary is available for DNM1P34 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

102 residues, UniProt reviewed canonical sequence.

>Q6PK57|DNM1P34
     1  MPSCSPQQAS KAEENGSNSF MHSMVPQLEW QMETTQSLVD SYVAIVNKTV WDLMVGLTPK
    61  TIMHLMINNN KEFIFSELLA NLYLHGDKNM LMEESAEQAQ RS

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against DNM1P34 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.51

OntologyGO

Molecular functions

Protein domainsUniProt · Pfam · InterPro

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads DNM1P34 as an antibody target. Whether an autoantibody or antibody against DNM1P34 could matter depends on whether native DNM1P34 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

DNM1P34 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label DNM1P34 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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