Seroatlas · Human Serome Atlas

DIP2C-AS1

Putative uncharacterized protein DIP2C-AS1

Also known as: PRR26_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8N8Z3
Gene: DIP2C-AS1
Canonical length: 221 aa

OverviewNCBI Gene

No narrative summary is available for DIP2C-AS1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

221 residues, UniProt reviewed canonical sequence.

>Q8N8Z3|DIP2C-AS1
     1  MESSRWDKDP PGERRPQQSQ HWRARDHGAR GCGPRQPTAT ASPRPGLWIT PAHGSHTPQT
    61  NTRRTQADNI FIYESWLIHH GTQMSSVLPQ PPLVRGPWHN TNSPWDSWAS RGKLRVCPCR
   121  TPRLHSSGCF SSKAGTALSP SLPVPGLRPQ PPFLQKPLSI LAPATPPALV SPTPPKLSPG
   181  QLSPHSVNVH WGPQGHLHLP RSGTTVLHAY LQTLSSPASH Q

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against DIP2C-AS1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.72

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 4% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads DIP2C-AS1 as an antibody target. Whether an autoantibody or antibody against DIP2C-AS1 could matter depends on whether native DIP2C-AS1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

DIP2C-AS1 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label DIP2C-AS1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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