Seroatlas · Human Serome Atlas

CXorf1

Putative transmembrane protein CXorf1

Also known as: CX001_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: O96002
Gene: CXorf1
Canonical length: 111 aa

OverviewNCBI Gene

No narrative summary is available for CXorf1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

111 residues, UniProt reviewed canonical sequence.

>O96002|CXorf1
     1  MYSRLFYLKS SYIIYFEPLF SNAIINILSF INSLASPLTI FCFALSAQAL STIFYFRIFI
    61  FIFHSWILLF HFYFTCSFKT YEHQHSKMVP AYRMQSPRAL PRTYLYVWPY K

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against CXorf1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 2
Mean surface accessibility (rSASA): 0.5

OntologyGO

Cellular components

membrane

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads CXorf1 as an antibody target. Whether an autoantibody or antibody against CXorf1 could matter depends on whether native CXorf1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

CXorf1 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label CXorf1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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