Seroatlas · Human Serome Atlas

CTAGE3P

Putative cTAGE family member 3

Also known as: CTGE3_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8IX95
Gene: CTAGE3P
Canonical length: 158 aa

OverviewNCBI Gene

No narrative summary is available for CTAGE3P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

158 residues, UniProt reviewed canonical sequence.

>Q8IX95|CTAGE3P
     1  MTFKGFQMNE EKLEIGIQDA SSENCQLQES QKQLLQEAEV WKEQVSELNK QKITFEDSKV
    61  HAEQVLNDKE NHIETLTERL LKIKDQAAVL EEDITDDGNL ELEMNSELKD GAYLDNPPKG
   121  ALKKLIHAAK LNASLTTLEG ERNQFIFSYL KLIKPGRA

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against CTAGE3P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.54

Protein domainsUniProt · Pfam · InterPro

cTAGE and MIA/OTOR

KeywordsUniProt

Coiled coil

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads CTAGE3P as an antibody target. Whether an autoantibody or antibody against CTAGE3P could matter depends on whether native CTAGE3P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

CTAGE3P is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label CTAGE3P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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