Seroatlas · Human Serome Atlas

COX7A2P2

Putative cytochrome c oxidase subunit 7A3, mitochondrial

Also known as: COX7S_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: O60397
Gene: COX7A2P2
Canonical length: 106 aa

OverviewNCBI Gene

No narrative summary is available for COX7A2P2 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

106 residues, UniProt reviewed canonical sequence.

>O60397|COX7A2P2
     1  MLWNLLALHQ IGQRTISTAS HRHFKNKVPE KQKLFQEDDG IPLYLKGGIA DALLHRATMI
    61  LTVGGTAYAI YQLAVASFPN KGVTSIIPAI TWFTFIQLSM DQKSDK

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against COX7A2P2 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Other membrane
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.53

DiseaseUniProt · ClinVar · IEDB · PubMed

Four sources answering four different questions about COX7A2P2.

Disease | ImmuneIEDB

Conditions an epitope on COX7A2P2 was assayed in.

human immunodeficiency virus infectious disease T cell

OntologyGO

Biological processes

Cellular components

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads COX7A2P2 as an antibody target. Whether an autoantibody or antibody against COX7A2P2 could matter depends on whether native COX7A2P2 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

COX7A2P2 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label COX7A2P2 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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