COL25A1-DT
Putative uncharacterized protein COL25A1-DT
Also known as: COLDT_HUMAN
Protein identityUniProt · HPA
- UniProt accession
- Q6ZST2
- Gene
- COL25A1-DT
- Canonical length
- 131 aa
OverviewNCBI Gene
No narrative summary is available for COL25A1-DT in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
131 residues, UniProt reviewed canonical sequence.
>Q6ZST2|COL25A1-DT
1 MLLLNQTLAT TEKQTALQAA EKFVDELCIS YSAKKGRGYA RKRQKNLLAT LQAYKPQNPK
61 DAPVNCDKCG KPGNVKNDCP GSMRKPARPC PICGGDHWRV DCPQRCRSLG PKPVSQVSNR
121 IDGPQGSCPW LLocalizationUniProt · AlphaFold · HPA
Whether an antibody against COL25A1-DT can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Unknown
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.54
OntologyGO
Molecular functions
Protein domainsUniProt · Pfam · InterPro
KeywordsUniProt
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads COL25A1-DT as an antibody target. Whether an autoantibody or antibody against COL25A1-DT could matter depends on whether native COL25A1-DT is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
COL25A1-DT is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label COL25A1-DT as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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