CHCHD2P9
Putative coiled-coil-helix-coiled-coil-helix domain-containing protein CHCHD2P9, mitochondrial
Also known as: CHCH9_HUMAN
Protein identityUniProt · HPA
OverviewNCBI Gene
No narrative summary is available for CHCHD2P9 in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
151 residues, UniProt reviewed canonical sequence.
>Q5T1J5|CHCHD2P9
1 MPRGSRSRTS RMAPPASRAP QMRAAPRPAP VAQPPAAAPP SAVGSSAAAP RQPGLMAQMA
61 TTAAGVAVGS AVGHTQGHAV TGGFSGGSNA EPARPDIAYQ EPQGTQPAQQ QQPCFYGIKQ
121 FLECAQNQGD IKLCEDFSKV LKQCRLAKGL ALocalizationUniProt · AlphaFold · HPA
Whether an antibody against CHCHD2P9 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Intracellular
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.67
OntologyGO
Biological processes
Molecular functions
Cellular components
Protein domainsUniProt · Pfam · InterPro
KeywordsUniProt
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads CHCHD2P9 as an antibody target. Whether an autoantibody or antibody against CHCHD2P9 could matter depends on whether native CHCHD2P9 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
CHCHD2P9 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label CHCHD2P9 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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