CFAP97D2
Uncharacterized protein CFAP97D2
Also known as: C97D2_HUMAN
Cross-references: UniProt · Ensembl · Human Protein Atlas · GeneCards · NCBI Gene
Protein identityUniProt · HPA
- UniProt accession
- A0A1B0GU71
- Gene
- CFAP97D2
- Ensembl
- ENSG00000283361
- Chromosome
- 13
- Canonical length
- 98 aa
- Protein class
- Predicted intracellular proteins
OverviewNCBI Gene
No narrative summary is available for CFAP97D2 in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
98 residues, UniProt reviewed canonical sequence.
>A0A1B0GU71|CFAP97D2
1 MHGAPRLTFP CASEYLWHAR EKAYQDHRRK VQSAQPLVDT RAPLTFRHLH LKLKRLKLEE
61 ERLSVIERDN RLLLEKVASV MRTRGQTDSK NNSKHRRKLocalizationUniProt · AlphaFold · HPA
Whether an antibody against CFAP97D2 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Unknown
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.58
- Highest tissue expression
- 18 nTPM
Expression across tissuesHPA
Tissue
- fallopian tube: 18 nTPM
- choroid plexus: 7.1 nTPM
- pancreas: 6 nTPM
- hypothalamus: 2.6 nTPM
- basal ganglia: 2.5 nTPM
- hippocampal formation: 2.1 nTPM
Single-cell type
- ependymal cells: 205 nCPM
- fallopian tube ciliated cells: 138 nCPM
- respiratory ciliated cells: 97 nCPM
- early primary spermatocytes: 80 nCPM
- pancreatic acinar cells: 44 nCPM
- endometrial ciliated cells: 39 nCPM
Immune cell
- naive CD8 T-cell: 4 nTPM
- naive CD4 T-cell: 0.3 nTPM
- total PBMC: 0.3 nTPM
- gdT-cell: 0.2 nTPM
- basophil: 0 nTPM
- classical monocyte: 0 nTPM
Brain region
- medulla oblongata: 8.5 nTPM
- spinal cord: 7.1 nTPM
- choroid plexus: 6.4 nTPM
- midbrain: 5.9 nTPM
- white matter: 4.9 nTPM
- pons: 3.1 nTPM
Protein domainsUniProt · Pfam · InterPro
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads CFAP97D2 as an antibody target. Whether an autoantibody or antibody against CFAP97D2 could matter depends on whether native CFAP97D2 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
CFAP97D2 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label CFAP97D2 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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