Seroatlas · Human Serome Atlas

CFAP144P1

Protein CFAP144P1

Also known as: F183B_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q6ZVS7
Gene: CFAP144P1
Canonical length: 135 aa

OverviewNCBI Gene

No narrative summary is available for CFAP144P1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

135 residues, UniProt reviewed canonical sequence.

>Q6ZVS7|CFAP144P1
     1  MAGHPKERVV TDEVHQNQIL RELYLKELRT QKLHTQYHVN PLRKVHRITR KPMSWHDNLE
    61  EPADARFLNL IHHAAQGPTK KYPEAQTENQ EIGWDSEALV DPERRDHRMN HFRVYSDITL
   121  YKAKMWSLGE DDRHK

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against CFAP144P1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.57

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 4% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

OntologyGO

Cellular components

ciliary base

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads CFAP144P1 as an antibody target. Whether an autoantibody or antibody against CFAP144P1 could matter depends on whether native CFAP144P1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

CFAP144P1 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label CFAP144P1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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