Seroatlas · Human Serome Atlas

CDRT15P3

Putative uncharacterized protein CDRT15P3

Also known as: CB27B_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: P0DPF6
Gene: CDRT15P3
Canonical length: 209 aa

OverviewNCBI Gene

No narrative summary is available for CDRT15P3 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

209 residues, UniProt reviewed canonical sequence.

>P0DPF6|CDRT15P3
     1  MFVRPESGEQ GPETLAPASG AEIQRFPVPA VEPVPAPGAD SPPGTALELE EAPEPSCRCP
    61  GTAQDQPSEE LPDFMAPPVE PPASALELKV WLELEVAERG GQHSSSQQLP HCSQSWAQWK
   121  LWRQRPGFAI WAPLPHWRGT SLIQQSSSPA AEGPAATAAG AVCLPAGGAG EQEKEPVSRG
   181  SSRSSCSQRR PPPPGMEVCP QLGIWAICP

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against CDRT15P3 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.7

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 3% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads CDRT15P3 as an antibody target. Whether an autoantibody or antibody against CDRT15P3 could matter depends on whether native CDRT15P3 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

CDRT15P3 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label CDRT15P3 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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