Seroatlas · Human Serome Atlas

CCNYL3

Putative cyclin-Y-like protein 3

Also known as: CCYL3_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: P0C7X3
Gene: CCNYL3
Canonical length: 344 aa

OverviewNCBI Gene

No narrative summary is available for CCNYL3 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

344 residues, UniProt reviewed canonical sequence.

>P0C7X3|CCNYL3
     1  MACAVFQIPP WHLDRKYGSC STILLDNSTA SQPDLRHTLE RYANRSLAIF EEPVHPLPQE
    61  KLPGKSFKHD PKRNCIFRHF CTLFQVIKLT APCAIVALVY IKRLLTSANI DLCPTNWKKI
   121  VLGTMLLASK VWRNHGLWSV DDSQNSKDTA VENMSKMEKC FLELLEFNIH VSASVYAKYY
   181  FDLCALANDH DLYFLFSFLH KDKAQKLEGH TSQHSLSLGP CRVGMENYAT YSPLSSQPVL
   241  GALSLAEVLP QEIKQEIHQV LMDHGVPCHY TCFLLHPEDS TLERFLVLHS IQGLQEDSVL
   301  CKVEIHGLSP QPQTYQSHFR SPSLAELLNR ISGTCRNHFA GMQK

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against CCNYL3 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Cell surface
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.44

OntologyGO

Biological processes

regulation of canonical Wnt signaling pathway

Cellular components

plasma membrane

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Cyclin

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads CCNYL3 as an antibody target. Whether an autoantibody or antibody against CCNYL3 could matter depends on whether native CCNYL3 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

CCNYL3 is annotated at the cell surface, where native CCNYL3 is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label CCNYL3 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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