Seroatlas · Human Serome Atlas

CCNYL2

Cyclin-Y-like protein 2

Also known as: CCYL2_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q5T2Q4
Gene: CCNYL2
Canonical length: 361 aa

OverviewNCBI Gene

No narrative summary is available for CCNYL2 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

361 residues, UniProt reviewed canonical sequence.

>Q5T2Q4|CCNYL2
     1  MGNILTCCVC PRASPGLHQH QGLVCHCESE IYEAAAGDLI AGVPVAAAVE PGEVTFVAGE
    61  GLHMHHICER EMPEDIPLEP NPSDHPKAST IFLRKSQTDV QEKKKKQLCK VSTEHFTQQY
   121  SSCSTIFLDD SIASQPHLTM TLKSCDLGTI LSYQAKRDAH RSLGIFDEQL HPLTVRKEVL
   181  EEYFKYDPEH KLIFRFVRTL FKAMRLTAEF AIVSLIYIER LVSYADIDIC PTNWKRIVLG
   241  AILLASKVWS DMAVWNEDYC KLFKNITVEE MNELERQFLK LINYNNSITN SVYSRFYFDL
   301  RTLAHNNGLY SPVYLLDRER AWKLEAFSRM EQDKVFYSAA KNGSLSADDL IHLQRAKAIL
   361  F

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against CCNYL2 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Cell surface
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.4

OntologyGO

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Cyclin

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads CCNYL2 as an antibody target. Whether an autoantibody or antibody against CCNYL2 could matter depends on whether native CCNYL2 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

CCNYL2 is annotated at the cell surface, where native CCNYL2 is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label CCNYL2 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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