Seroatlas · Human Serome Atlas

CCNYL1B

Cyclin-Y-like protein 1B

Also known as: CYL1B_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A0A8V8TMC4
Gene: CCNYL1B
Canonical length: 285 aa

OverviewNCBI Gene

No narrative summary is available for CCNYL1B in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

285 residues, UniProt reviewed canonical sequence.

>A0A8V8TMC4|CCNYL1B
     1  MPKNFASDCP GESTLFLRKY QMSVQEKRSS SHLYYIPPWH LDRKYGSCST ILLDNSTASQ
    61  PDLRHTLESV ALAIYYNIKH RYANRSLAIF EEPVHPLPQE KLPGKSFKHD PKRNCIFRHF
   121  CTLFQVIKLT APCAIVALVY IKRLLTSANI DLCPTNWKKI VLGTMLLASK VWRNHGLWSV
   181  DDSQNSKDTA VENMSKMEKC FLELLEFNIH VSASVYAKYY FDLCALANDH DLYFLFSFLH
   241  KDKAQKLEAM SRLCEYKDLH QDAAALKRVI SMNFIGIGCS NAILS

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against CCNYL1B can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Cell surface
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.37

OntologyGO

Biological processes

regulation of canonical Wnt signaling pathway

Cellular components

plasma membrane

Protein domainsUniProt · Pfam · InterPro

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads CCNYL1B as an antibody target. Whether an autoantibody or antibody against CCNYL1B could matter depends on whether native CCNYL1B is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

CCNYL1B is annotated at the cell surface, where native CCNYL1B is exposed to circulating antibodies and is a prime autoantibody target that could block, deplete, or overstimulate it.

Annotation status

The present source text does not explicitly label CCNYL1B as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Loading the interactive Seroatlas protein explorer...