CCDC201
Coiled-coil domain-containing protein 201
Also known as: CC201_HUMAN
Cross-references: UniProt · Ensembl · Human Protein Atlas · GeneCards · NCBI Gene
Protein identityUniProt · HPA
- UniProt accession
- A0A1B0GTI1
- Gene
- CCDC201
- Ensembl
- ENSG00000283247
- Chromosome
- 7
- Canonical length
- 187 aa
- Protein class
- Predicted intracellular proteins
OverviewNCBI Gene
No narrative summary is available for CCDC201 in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
187 residues, UniProt reviewed canonical sequence.
>A0A1B0GTI1|CCDC201
1 MEPGVQDLGL SSSEDESPSL AIRSPTLRKP LKHSTPEEAA LGWSPRPSGG ASYLSGSPMP
61 AHFSQDLASH PAGVSPPATV RKRRLSTLWA SKESSLDLSA PGEEPPTSAS LTQRQRQRQQ
121 QQQQQESLRA KSWAQNPGLP GILNTTGRKR RDPKKRAAAM ERVRQWEIYV LQNIEEATQH
181 ELTIEDDLocalizationUniProt · AlphaFold · HPA
Whether an antibody against CCDC201 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Unknown
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.67
- Highest tissue expression
- 0.8 nTPM
Expression across tissuesHPA
Tissue
- placenta: 0.8 nTPM
- breast: 0.7 nTPM
- ovary: 0.4 nTPM
- epididymis: 0.3 nTPM
- bone marrow: 0.2 nTPM
- retina: 0.2 nTPM
Single-cell type
- oocytes: 41 nCPM
- cytotrophoblasts: 4.8 nCPM
- migrating cytotrophoblasts: 1.7 nCPM
- retinal amacrine cells: 0.7 nCPM
- breast lactating cells: 0.4 nCPM
- prostatic club cells: 0.4 nCPM
Immune cell
- basophil: 0 nTPM
- classical monocyte: 0 nTPM
- eosinophil: 0 nTPM
- gdT-cell: 0 nTPM
- intermediate monocyte: 0 nTPM
- MAIT T-cell: 0 nTPM
Brain region
- cerebral cortex: 1.7 nTPM
- amygdala: 1.5 nTPM
- cerebellum: 1.5 nTPM
- hypothalamus: 1.5 nTPM
- basal ganglia: 1.3 nTPM
- medulla oblongata: 1.3 nTPM
KeywordsUniProt
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads CCDC201 as an antibody target. Whether an autoantibody or antibody against CCDC201 could matter depends on whether native CCDC201 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
CCDC201 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label CCDC201 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
Loading the interactive Seroatlas protein explorer...