Seroatlas · Human Serome Atlas

CCDC201

Coiled-coil domain-containing protein 201

Also known as: CC201_HUMAN

Cross-references: UniProt · Ensembl · Human Protein Atlas · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
A0A1B0GTI1
Gene
CCDC201
Ensembl
ENSG00000283247
Chromosome
7
Canonical length
187 aa
Protein class
Predicted intracellular proteins

OverviewNCBI Gene

No narrative summary is available for CCDC201 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

187 residues, UniProt reviewed canonical sequence.

>A0A1B0GTI1|CCDC201
     1  MEPGVQDLGL SSSEDESPSL AIRSPTLRKP LKHSTPEEAA LGWSPRPSGG ASYLSGSPMP
    61  AHFSQDLASH PAGVSPPATV RKRRLSTLWA SKESSLDLSA PGEEPPTSAS LTQRQRQRQQ
   121  QQQQQESLRA KSWAQNPGLP GILNTTGRKR RDPKKRAAAM ERVRQWEIYV LQNIEEATQH
   181  ELTIEDD

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against CCDC201 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.67
Highest tissue expression
0.8 nTPM

Expression across tissuesHPA

Tissue

  • placenta: 0.8 nTPM
  • breast: 0.7 nTPM
  • ovary: 0.4 nTPM
  • epididymis: 0.3 nTPM
  • bone marrow: 0.2 nTPM
  • retina: 0.2 nTPM

Single-cell type

  • oocytes: 41 nCPM
  • cytotrophoblasts: 4.8 nCPM
  • migrating cytotrophoblasts: 1.7 nCPM
  • retinal amacrine cells: 0.7 nCPM
  • breast lactating cells: 0.4 nCPM
  • prostatic club cells: 0.4 nCPM

Immune cell

  • basophil: 0 nTPM
  • classical monocyte: 0 nTPM
  • eosinophil: 0 nTPM
  • gdT-cell: 0 nTPM
  • intermediate monocyte: 0 nTPM
  • MAIT T-cell: 0 nTPM

Brain region

  • cerebral cortex: 1.7 nTPM
  • amygdala: 1.5 nTPM
  • cerebellum: 1.5 nTPM
  • hypothalamus: 1.5 nTPM
  • basal ganglia: 1.3 nTPM
  • medulla oblongata: 1.3 nTPM

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads CCDC201 as an antibody target. Whether an autoantibody or antibody against CCDC201 could matter depends on whether native CCDC201 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

CCDC201 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label CCDC201 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/CCDC201. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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