Seroatlas · Human Serome Atlas

C7orf78

Putative uncharacterized protein C7orf78

Also known as: CG078_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A0A1B0GVB3
Gene: C7orf78
Canonical length: 256 aa

OverviewNCBI Gene

No narrative summary is available for C7orf78 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

256 residues, UniProt reviewed canonical sequence.

>A0A1B0GVB3|C7orf78
     1  MIPPCENAPH IIYHESQRGT RDRDIAKRLQ YPSRQDLNSK WKKSVLQPPQ CKMKVNVWEI
    61  KPPDFSYKLY TSLRIPERSS KPIKEEKRRK KISFPETMLH LPSIRNHPKE VTAPKFITTF
   121  PHLDLQKAKL MFVKSGQYPR GVYVNPKPHD FRQYQPGLPN FETTYEKDPF GLKFKSQHLS
   181  TVHGYQLPKD DKQKTSTERF ITHKHCECTW DSKLILTKAP WPVRSASYTR HRRQRDAYSA
   241  FMDRVEEKFT KICKSR

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against C7orf78 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.66

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads C7orf78 as an antibody target. Whether an autoantibody or antibody against C7orf78 could matter depends on whether native C7orf78 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

C7orf78 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label C7orf78 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Loading the interactive Seroatlas protein explorer...