Seroatlas · Human Serome Atlas

C5orf67

Uncharacterized protein C5orf67

Also known as: CE067_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: F2Z3F1
Gene: C5orf67
Canonical length: 127 aa

OverviewNCBI Gene

No narrative summary is available for C5orf67 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

127 residues, UniProt reviewed canonical sequence.

>F2Z3F1|C5orf67
     1  MKRIFYKHRK RRAPVFKEPE HGYQSLPELV LVPAQPLVCL GDYRTPDPGG LFPWSLRLMM
    61  PGAWTKLPGD GGSVPEKGKH GILGAQGQEH PGLNVSSPFS SPWTCYLSGH QPQNNNSPEL
   121  QVKEILL

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against C5orf67 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.67

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads C5orf67 as an antibody target. Whether an autoantibody or antibody against C5orf67 could matter depends on whether native C5orf67 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

C5orf67 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label C5orf67 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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