Seroatlas · Human Serome Atlas

C18orf15

Putative uncharacterized protein C18orf15

Also known as: CR015_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q96N68
Gene: C18orf15
Canonical length: 181 aa

OverviewNCBI Gene

No narrative summary is available for C18orf15 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

181 residues, UniProt reviewed canonical sequence.

>Q96N68|C18orf15
     1  MQGQGALKES HIHLPTEQPE ASLVLQGQLA ESSALGPKGA LRPQAQSPDV PVSWWQGSGK
    61  RLSHRLPHIC SQPPLGPFLP LTWPSCGFFG LGGAASASLG LEVLQDSVST WARGPCCPVH
   121  PQSLTVVCMC ACMCVCVHVC ACVYVCMCVL VCMCACACMR AHRYFLMDCA GICSPHGPGT
   181  Q

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against C18orf15 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 1
Mean surface accessibility (rSASA): 0.66

OntologyGO

Cellular components

membrane

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads C18orf15 as an antibody target. Whether an autoantibody or antibody against C18orf15 could matter depends on whether native C18orf15 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

C18orf15 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label C18orf15 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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