C0HM83
Protein SHMOOSE
Also known as: SHMOS_HUMAN
Protein identityUniProt · HPA
OverviewNCBI Gene
No narrative summary is available for C0HM83 in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
58 residues, UniProt reviewed canonical sequence.
>C0HM83|C0HM83
1 MPPCLTTWLS QLLKDNSYPL VLGPKNFGAT PNKSNNHAHY YNHPNPDFPN SPHPYHPRLocalizationUniProt · AlphaFold · HPA
Whether an antibody against C0HM83 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Intracellular
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.63
OntologyGO
Cellular components
Protein domainsUniProt · Pfam · InterPro
- SHMOOSE
KeywordsUniProt
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads C0HM83 as an antibody target. Whether an autoantibody or antibody against C0HM83 could matter depends on whether native C0HM83 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
C0HM83 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label C0HM83 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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