BCORP1
Putative BCoR-like protein 2
Also known as: BCOR2_HUMAN
Protein identityUniProt · HPA
OverviewNCBI Gene
No narrative summary is available for BCORP1 in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
145 residues, UniProt reviewed canonical sequence.
>Q8N888|BCORP1
1 MKEKLSKKRA EVKGNRSWLE EFLKPSDNEE GPPPKNKVLS NNASSQKPTH SSCIPLLRLP
61 DKQQKVNESI KTDMLCTDKE EECPAASLLQ KYTNNSEKPS GKRQCKTKHL ISQDLRQGFL
121 LTGKCYVENA DGKIPLGTCF LLGLILocalizationUniProt · AlphaFold · HPA
Whether an antibody against BCORP1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Unknown
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.7
Protein domainsUniProt · Pfam · InterPro
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads BCORP1 as an antibody target. Whether an autoantibody or antibody against BCORP1 could matter depends on whether native BCORP1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
BCORP1 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label BCORP1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
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