Seroatlas · Human Serome Atlas

ASB16-AS1

Putative uncharacterized protein ASB16-AS1

Also known as: ASAS1_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q495Z4
Gene: ASB16-AS1
Canonical length: 193 aa

OverviewNCBI Gene

No narrative summary is available for ASB16-AS1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

193 residues, UniProt reviewed canonical sequence.

>Q495Z4|ASB16-AS1
     1  MSGPPSAPQG ALAAPRSPAV RRKGLQAPSW GSPGRPAAHS PWACGPPHWG PQRGPRNAAA
    61  ARPGPRSRWH KRCAAACGAC ARPPGHQLQP PGAGAPQPGV ACSYLGPRPQ RTPCSAQSRP
   121  GWCAGPRRRH APGTEPHVAP GRAPPPRAGA SPGSRLLPGS PSLLLPAATW RTWGQESKVL
   181  RKILKAWDPF SLL

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against ASB16-AS1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.72

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads ASB16-AS1 as an antibody target. Whether an autoantibody or antibody against ASB16-AS1 could matter depends on whether native ASB16-AS1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

ASB16-AS1 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label ASB16-AS1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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