Seroatlas · Human Serome Atlas

ARB2BP

Putative protein ARB2BP

Also known as: ARB2P_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A6NC97
Gene: ARB2BP
Canonical length: 362 aa

OverviewNCBI Gene

No narrative summary is available for ARB2BP in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

362 residues, UniProt reviewed canonical sequence.

>A6NC97|ARB2BP
     1  MTQELSFQKF IEQSDLLGEL KYDFNEKDEF RHTETQRPFV FNYYENVLEK NSKRYQALGH
    61  LLEQYIYELL EKVCKLEKVY IPPEADKEEP RSFFFMSEKA LTNHHSALLI LLQDHGVFRA
   121  GQWSQQAIIH HGLQHGSQIP CIQMALQAHY DVIVLNPNDN FVEPKVEKEW KGLLTQNIES
   181  SSLKMVQGGS FFSLQHPPKC IPKRCSNTPE EHTAYIWDYF ISKTEGKDIA FIVHGYGGLV
   241  FMDLLVRRRW EVMSKVYAVA LIDSEHHVGH QLGSDVQLLA WIKHHCREWV TSPKPLDKPA
   301  ATVFKKEFPM VSAGTEKYIL APSSSLQSIF KYFKKALKAR TTINFSRMPI VTRSSTKRKQ
   361  SA

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against ARB2BP can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 1
Mean surface accessibility (rSASA): 0.29

OntologyGO

Biological processes

regulatory ncRNA-mediated heterochromatin formation

Cellular components

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads ARB2BP as an antibody target. Whether an autoantibody or antibody against ARB2BP could matter depends on whether native ARB2BP is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

ARB2BP is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label ARB2BP as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Loading the interactive Seroatlas protein explorer...