AQP5-AS1
Micropeptide inhibiting actin cytoskeleton
Also known as: MIAC_HUMAN
Protein identityUniProt · HPA
- UniProt accession
- A0A7L8Y648
- Gene
- AQP5-AS1
- Canonical length
- 51 aa
OverviewNCBI Gene
No narrative summary is available for AQP5-AS1 in this catalog release; identity and structured annotations are shown without generated factual claims.
Canonical amino-acid sequenceUniProt
51 residues, UniProt reviewed canonical sequence.
>A0A7L8Y648|AQP5-AS1
1 MERAGVPGFS PRRSSVEAKM QSTSCSVRKS STVTAWPAVV LLLSWGQRRG GLocalizationUniProt · AlphaFold · HPA
Whether an antibody against AQP5-AS1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.
- Antibody reachability
- Unknown
- Secreted
- No
- Transmembrane segments
- 0
- Mean surface accessibility (rSASA)
- 0.69
OntologyGO
Biological processes
Protein domainsUniProt · Pfam · InterPro
- Micropeptide inhibiting actin cytoskeleton
- Micropeptide inhibiting actin cytoskeleton
Antibody and autoantibody relevanceSeroatlas analysis
Seroatlas reads AQP5-AS1 as an antibody target. Whether an autoantibody or antibody against AQP5-AS1 could matter depends on whether native AQP5-AS1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.
AQP5-AS1 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.
Annotation status
The present source text does not explicitly label AQP5-AS1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.
Loading the interactive Seroatlas protein explorer...