Seroatlas · Human Serome Atlas

ANP32CP

Putative uncharacterized protein ANP32CP

Also known as: AN32C_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: O43423
Gene: ANP32CP
Canonical length: 234 aa

OverviewNCBI Gene

No narrative summary is available for ANP32CP in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

234 residues, UniProt reviewed canonical sequence.

>O43423|ANP32CP
     1  MEMGRRIHSE LRNRAPSDVK ELALDNSRSN EGKLEALTDE FEELEFLSKI NGGLTSISDL
    61  PKLKLRKLEL RVSGGLEVLA EKCPNLTHLY LSGNKIKDLS TIEPLKQLEN LKSLDLFNCE
   121  VTNLNDYGEN VFKLLLQLTY LDSCYWDHKE APYSDIEDHV EGLDDEEEGE HEEEYDEDAQ
   181  VVEDEEGEEE EEEGEEEDVS GGDEEDEEGY NDGEVDGEED EEELGEEERG QKRK

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against ANP32CP can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.44

OntologyGO

Biological processes

Molecular functions

histone binding

Cellular components

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads ANP32CP as an antibody target. Whether an autoantibody or antibody against ANP32CP could matter depends on whether native ANP32CP is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

ANP32CP is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label ANP32CP as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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