Seroatlas · Human Serome Atlas

ANKRD36BP1

Putative ankyrin repeat domain-containing protein 26-like 1

Also known as: A26L1_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q96IX9
Gene: ANKRD36BP1
Canonical length: 119 aa

OverviewNCBI Gene

No narrative summary is available for ANKRD36BP1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

119 residues, UniProt reviewed canonical sequence.

>Q96IX9|ANKRD36BP1
     1  MGTRTLQFEI SDSHEKEEDL LHKNHLMQDE IARLRLEIHT IKNQILEKKY LKDIEIIKRK
    61  HEDLQKALKQ NGEKSTKTIA HYSGQLTALT DENTMLRSKL EKEKQSRQRL TKWNHTIVD

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against ANKRD36BP1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.49

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 7% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Coiled coil

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads ANKRD36BP1 as an antibody target. Whether an autoantibody or antibody against ANKRD36BP1 could matter depends on whether native ANKRD36BP1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

ANKRD36BP1 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label ANKRD36BP1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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