Seroatlas · Human Serome Atlas

ANKRD20A5P

Putative ankyrin repeat domain-containing protein 20A5

Also known as: A20A5_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A0PJZ0
Gene: ANKRD20A5P
Canonical length: 165 aa

OverviewNCBI Gene

No narrative summary is available for ANKRD20A5P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

165 residues, UniProt reviewed canonical sequence.

>A0PJZ0|ANKRD20A5P
     1  MKLFGFRSRR GQTVLGSIDH LYTGSGYRIR YSELQKIHKA AVKGDAAEME RCLARRSGDL
    61  DALDKQHRTA LHLACASGHV KVVTLLVNRK CQIDIYDKEN RTPLIQAVHC QEEACAVILL
   121  EHGANPNLKD IYGNTALHYA VYSESTSLAE KLLFHGENIE ALDKV

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against ANKRD20A5P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.34

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads ANKRD20A5P as an antibody target. Whether an autoantibody or antibody against ANKRD20A5P could matter depends on whether native ANKRD20A5P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

ANKRD20A5P is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label ANKRD20A5P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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