Seroatlas · Human Serome Atlas

ANKRD20A3P

Putative ankyrin repeat domain-containing protein 20A3

Also known as: A20A3_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
Q5VUR7
Gene
ANKRD20A3P
Canonical length
823 aa

OverviewNCBI Gene

No narrative summary is available for ANKRD20A3P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

823 residues, UniProt reviewed canonical sequence.

>Q5VUR7|ANKRD20A3P
     1  MKLFGFGSRR GQTAQGSIDH VYTGSGYRIR DSELQKIHRA AVKGDAAEVE RCLARRSGDL
    61  DALDKQHRTA LHLACASGHV QVVTLLVNRK CQIDVCDKEN RTPLIQAVHC QEEACAVILL
   121  EHGANPNLKD IYGNTALHYA VYSESTSLAE KLLSHGAHIE ALDKDNNTPL LFAIICKKEK
   181  MVEFLLKRKA SSHAVDRLRR SALMLAVYYD SPGIVNILLK QNIDVFAQDM CGRDAEDYAI
   241  SHHLTKIQQQ ILEHKKKILK KEKSDVGSSD ESAVSIFHEL RVDSLPASDD KDLNVATKQC
   301  VPEKVSEPLP GSSHEKGNRI VNGQGEGPPA KHPSLKPSTE VEDPAVKGAV QRKNVQTLRA
   361  EQALPVASEE EQERHERSEK KQPQVKEGNN TNKSEKIQLS ENICDSTSSA AAGRLTQQRK
   421  IGKTYPQQFP KKLKEEHDRC TLKQENEEKT NVNMLYKKNR EELERKEKQY KKEVEAKQLE
   481  PTVQSLEMKS KTARNTPNRD FHNHEEMKGL MDENCILKAD IAILRQEICT MKNDNLEKEN
   541  KYLKDIKIVK ETNAALEKYI KLNEEMITET AFRYQQELNY LKAENTRLNA ELLKEKESKK
   601  RLEADIESYQ SRLAAAISKH SESVKTERNL KLALERTRDV SVQVEMSSAI SKVKDENEFL
   661  TEQLSETQIK FNALKDKFRK TRDSLRKKSL ALETVQNDLS QTQQQTQEMK EMYQNAEAKV
   721  NNSTGKWNCV EERICHLQRE NAWLVQQLDD VHQKEDHKEI VTNIQRGFIE SGKKDLVLEE
   781  KSKKLMNECD HLKESLFQYE REKTEGVVSI KEDKYFQTSR KTI

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against ANKRD20A3P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.48

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 4% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads ANKRD20A3P as an antibody target. Whether an autoantibody or antibody against ANKRD20A3P could matter depends on whether native ANKRD20A3P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

ANKRD20A3P is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label ANKRD20A3P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/ANKRD20A3P. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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