Seroatlas · Human Serome Atlas

ANKRD20A12P

Putative ankyrin repeat domain-containing protein 20A12 pseudogene

Also known as: A2012_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q8NF67
Gene: ANKRD20A12P
Canonical length: 263 aa

OverviewNCBI Gene

No narrative summary is available for ANKRD20A12P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

263 residues, UniProt reviewed canonical sequence.

>Q8NF67|ANKRD20A12P
     1  MKEMYENAED KVNNSTGKWS CVEERICHLQ HENPCIEQQL DDVHQKEDHK EIVTNIQRGF
    61  IESGKKDLML EEKNKKLMNE CDHLKESLFQ YEREKAERVV VVRQLQQEAA DSLKKLTMLE
   121  SPLEGISHYH INLDETQVPK KKLFQVESQF DDLMVEKEAV SSKCVNLAKE NQVFQQKLLS
   181  MKKVQQECEK LEEDKKMLEE EILNLKTHME NSMVELSKLQ EYKSELDERA MQAVEKLEEI
   241  HLQEQAQYKK QLEQLNKDII QLH

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against ANKRD20A12P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.47

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Coiled coil

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads ANKRD20A12P as an antibody target. Whether an autoantibody or antibody against ANKRD20A12P could matter depends on whether native ANKRD20A12P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

ANKRD20A12P is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label ANKRD20A12P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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