Seroatlas · Human Serome Atlas

ANKRD19P

Putative ankyrin repeat domain-containing protein 19

Also known as: ANR19_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q9H560
Gene: ANKRD19P
Canonical length: 264 aa

OverviewNCBI Gene

No narrative summary is available for ANKRD19P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

264 residues, UniProt reviewed canonical sequence.

>Q9H560|ANKRD19P
     1  MRKLFSFGRR LGQALLDSMD QEYAGRGYHI RDWELRKIHR AAIKGDAAEV EHCLTRRFRD
    61  LDARDRKDRT VLHLTCAHGR VEVVTLLLSR RCQINIYDRL NRTPLMKAVH CQEEACAIIL
   121  LEHGANPNIK DIYSNTALHY AVYNKGTSLA EKLLSHHANI EALNEEGNTP LLFAINSRRQ
   181  QIVEFLLKNQ ANLHAIDNFR RTALMLAVQH NSSSIVSLLL QQNINIFSQD LFGQTAEDYA
   241  VCYNFRSIQQ QILEHKNKIL KSHL

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against ANKRD19P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.25

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 3% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads ANKRD19P as an antibody target. Whether an autoantibody or antibody against ANKRD19P could matter depends on whether native ANKRD19P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

ANKRD19P is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label ANKRD19P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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