Seroatlas · Human Serome Atlas

ANKRD13C-DT

Putative uncharacterized protein ANKRD13C-DT

Also known as: HHLA3_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
Q9XRX5
Gene
ANKRD13C-DT
Canonical length
114 aa

OverviewNCBI Gene

No narrative summary is available for ANKRD13C-DT in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

114 residues, UniProt reviewed canonical sequence.

>Q9XRX5|ANKRD13C-DT
     1  MFGACYKQPL KPSGSEPPAE ECRMTPRHAG CDVTEMQRIL SQPTFTEHLL RAVCTKLANM
    61  YSTSTDCREH CRRGMKAKQL KAEAGRSCQR KGVPIQTPRE HSWISCKKEF EANP

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against ANKRD13C-DT can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.58

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 5% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads ANKRD13C-DT as an antibody target. Whether an autoantibody or antibody against ANKRD13C-DT could matter depends on whether native ANKRD13C-DT is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

ANKRD13C-DT is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label ANKRD13C-DT as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/ANKRD13C-DT. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

Loading the interactive Seroatlas protein explorer...