Seroatlas · Human Serome Atlas

AGPAT4-IT1

Putative uncharacterized protein encoded by AGPAT4-IT1

Also known as: AGIT1_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q9H0P7
Gene: AGPAT4-IT1
Canonical length: 198 aa

OverviewNCBI Gene

No narrative summary is available for AGPAT4-IT1 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

198 residues, UniProt reviewed canonical sequence.

>Q9H0P7|AGPAT4-IT1
     1  MADTQCCPPP CEFISSAGTD LALGMGWDAT LCLLPFTGFG KCAGIWNHMD EEPDNGDDRG
    61  SRRTTGQGRK WAAHGTMAAP RVHTDYHPGG GSACSSVKVR SHVGHTGVFF FVDQDPLAVS
   121  LTSQSLIPPL IKPGLLKAWG FLLLCAQPSA NGHSLCCLLY TDLVSSHELS PFRALCLGPS
   181  DAPSACASCN CLASTYYL

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against AGPAT4-IT1 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.45

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads AGPAT4-IT1 as an antibody target. Whether an autoantibody or antibody against AGPAT4-IT1 could matter depends on whether native AGPAT4-IT1 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

AGPAT4-IT1 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label AGPAT4-IT1 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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