Seroatlas · Human Serome Atlas

AGAP7P

Putative Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 7

Also known as: AGAP7_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
Q5VUJ5
Gene
AGAP7P
Canonical length
663 aa

OverviewNCBI Gene

No narrative summary is available for AGAP7P in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

663 residues, UniProt reviewed canonical sequence.

>Q5VUJ5|AGAP7P
     1  MGNILTCRVH PSVSLEFDQQ QGSVCPSESE IYEAGAEDRM AGAPMAAAVQ PAEVTVEVGE
    61  DLHMHHVRDR EMPEALEFNP SANPEASTIF QRNSQTDVVE IRRSNCTNHV STVHFSQQYS
   121  LCSTIFLDDS TAIQHYLTMT IISVTLEIPH HITQRDADRS LSIPDEQLHS FAVSTVHITK
   181  NRNGGGSLNN YSSSIPSTPS TSQEDPQFSV PPTANTPTPV CKRSMRWSNL FTSEKGSDPD
   241  KERKAPENHA DTIGSGRAIP IKQGMLLKRS GKWLKTWKKK YVTLCSNGVL TYYSSLGDYM
   301  KYIHKKEIDL QTSTIKVPGK WPSLATLACT PISSSKSDGL SKDMDTGLGD SICFSPSISS
   361  TTIPKLNPPP SPHANKKKHL KKKSTNNFMI VSATGQTWHF EATTYEERDA WVQAIQSQIL
   421  ASLQSCESSK SKSQLTSQSE AMALQSIQNM RGNAHCVDCE TQNPKWASLN LGVLMCIECS
   481  GIHRSLGTRL SRVRSLELDD WPVELRKVMS SIGNDLANSI WEGSSQGRTK PTEKSTREEK
   541  ERWIRSKYEE KLFLAPLPCT ELSLGQQLLR ATADEDLQTA ILLLAHGSRE EVNETCGEGD
   601  GCTALHLACR KGNVVLAQLL IWYGVDVMAR DAHGNTALTY ARQASSQECI NVLLQYGCPD
   661  ECV

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against AGAP7P can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.49

Cancer expressionTCGA

Across TCGA tumor cohorts, this protein is over-expressed in roughly 4% of surveyed tumor types (aggregate summary; per-cohort expression, alteration, and survival load in the interactive view).

OntologyGO

Molecular functions

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads AGAP7P as an antibody target. Whether an autoantibody or antibody against AGAP7P could matter depends on whether native AGAP7P is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

AGAP7P is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label AGAP7P as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/AGAP7P. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

© 2026 · Seroatlas, Discover Oregon LLC · Terms of use

Loading the interactive Seroatlas protein explorer...