Seroatlas · Human Serome Atlas

ACOT7L

Putative cytosolic acyl coenzyme A thioester hydrolase-like

Also known as: BACHL_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: Q6ZUV0
Gene: ACOT7L
Canonical length: 252 aa
Quaternary structure: Homodimer

OverviewNCBI Gene

No narrative summary is available for ACOT7L in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

252 residues, UniProt reviewed canonical sequence.

>Q6ZUV0|ACOT7L
     1  MIKEAGAIIS TRHCNPQNGD RCVAALARVE CTHFLWPMCI GEVAHVSAEI TYTSKHSVEV
    61  QVNMMSENIL TGAKKLTNKA TLWYAPLSLT NVDKVLEEPP VVYFRQEQEE EGQKRYKTQK
   121  LERMETNWRN GDIVQPVLNP EPNTVSYSQS SLIHLVGPSD CTLHSFVHEG VTMKVMDEVA
   181  GILAARHCKT NLVTASMEAI NFDNKIRKGC IKTISGRMTF TSNKSVEIEV LVDADCVVDS
   241  SQKRYRAASV FT

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against ACOT7L can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Intracellular
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.31

OntologyGO

Biological processes

Molecular functions

Cellular components

Protein domainsUniProt · Pfam · InterPro

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads ACOT7L as an antibody target. Whether an autoantibody or antibody against ACOT7L could matter depends on whether native ACOT7L is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

ACOT7L is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label ACOT7L as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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