Seroatlas · Human Serome Atlas

A8MZ25

Putative uncharacterized protein FLJ38767

Also known as: YQ037_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A8MZ25
Gene: A8MZ25
Canonical length: 164 aa

OverviewNCBI Gene

No narrative summary is available for A8MZ25 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

164 residues, UniProt reviewed canonical sequence.

>A8MZ25|A8MZ25
     1  MGQKKTMGTE RSRGGKRGPQ PGAERPEEPG ATFSKKPPEG ARAPRCLSRP TAPKSGACLA
    61  RRRPPGSPCS IRDAPFHTGD DRFLARENFP NVLQPLPRMF AVQQAADFES QCPRRWDSRK
   121  RPSEGLPSAG WGRWRGRPIH LGLWVSGSVR RKVSGSHVSR SLHL

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against A8MZ25 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.72

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads A8MZ25 as an antibody target. Whether an autoantibody or antibody against A8MZ25 could matter depends on whether native A8MZ25 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

A8MZ25 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label A8MZ25 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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