Seroatlas · Human Serome Atlas

A8MV72

Putative UPF0607 protein ENSP00000382826

Also known as: YH009_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A8MV72
Gene: A8MV72
Canonical length: 311 aa

OverviewNCBI Gene

No narrative summary is available for A8MV72 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

311 residues, UniProt reviewed canonical sequence.

>A8MV72|A8MV72
     1  MLSARNSMMF GHLSPVRIPR LRGKFNLQLP SLDEQVIPAR LLKMEVRAEE PKEATEVKDQ
    61  VETQGQEDNK MGPCSNGEAA STSRPLETQG NLTSSWYNPR PLEGNVHLKS LTEKNQTDKA
   121  QVHAVSFYSK GHGVASSHSP AGGILPFGKP DPLPTVLPAP VPGCSLWPEK AALKVLGKDH
   181  LPSSPGLLMV GEDMQPKDPA VLGSSRSSPP RAAGHRSRKR KLSGPPLQLQ LTPPLQLRWD
   241  RDGGPPPAKL PCLSPEALLV GQASQREGRL QQGNMRKNMR VLSRTSKFRR RKQLLRRRKK
   301  TRQGRRGGSC L

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against A8MV72 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Unknown
Secreted: No
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.72

Protein domainsUniProt · Pfam · InterPro

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads A8MV72 as an antibody target. Whether an autoantibody or antibody against A8MV72 could matter depends on whether native A8MV72 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

A8MV72 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label A8MV72 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

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