Seroatlas · Human Serome Atlas

A8MUN3

Putative uncharacterized protein ENSP00000381830

Also known as: YQ048_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession: A8MUN3
Gene: A8MUN3
Canonical length: 132 aa

OverviewNCBI Gene

No narrative summary is available for A8MUN3 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

132 residues, UniProt reviewed canonical sequence.

>A8MUN3|A8MUN3
     1  MSFEYRHYKR EAKICTCRGG WAHVLLCIGV SQGACAEHLP HRPAVEKDVP GAGEVLFMCS
    61  WRIFPVASAS PSSSISGLAG HSVFLVPGLA AHPGSHSDQP PGVPSRRKSR LERWSPSVSR
   121  STSPPTEAPF CL

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against A8MUN3 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability: Secreted
Secreted: Yes
Transmembrane segments: 0
Mean surface accessibility (rSASA): 0.54

OntologyGO

Cellular components

extracellular region

KeywordsUniProt

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads A8MUN3 as an antibody target. Whether an autoantibody or antibody against A8MUN3 could matter depends on whether native A8MUN3 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

A8MUN3 is annotated as secreted, so native A8MUN3 circulates and is directly accessible to antibodies. Secreted and cell-surface proteins are the autoantibody targets most likely to act like drugs, blocking or depleting the native protein.

Annotation status

The present source text does not explicitly label A8MUN3 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Loading the interactive Seroatlas protein explorer...