Seroatlas · Human Serome Atlas

A8MUA0

Putative UPF0607 protein ENSP00000381514

Also known as: YB057_HUMAN

Cross-references: UniProt · GeneCards · NCBI Gene

Protein identityUniProt · HPA

UniProt accession
A8MUA0
Gene
A8MUA0
Canonical length
341 aa

OverviewNCBI Gene

No narrative summary is available for A8MUA0 in this catalog release; identity and structured annotations are shown without generated factual claims.

Canonical amino-acid sequenceUniProt

341 residues, UniProt reviewed canonical sequence.

>A8MUA0|A8MUA0
     1  MRLCLIPWNT GTPQRVLPPV VWSPPSRKKP VLSARNSRMF GYLSPVRIPR LRGKFNLQLP
    61  SLDEQVIPAR LPKMEVRAEE PKEATEVKDQ VQTQEQEDNK RGPCSNGEAA STSRPLETQG
   121  NLTSSWYNPR PLEGNVHLKS LTENNQTDKA QVHAVSFYSK GHGVASSHSP AGGILPFGKP
   181  DPLPTVLPAP VPGCSLWPEK AALKVLGKDH LPSSPGLLTV GEDMQPKDPA ALGSSRSSPP
   241  RAAGHRSRKR KLSGPPLQLQ PTPPLQLRWE RDERPPPAKL PCLSPEALLV GQASQREGRL
   301  QQGNMRKNMR VLSRTSKFRR LRQLLRRRKK RQQVRSISAC T

LocalizationUniProt · AlphaFold · HPA

Whether an antibody against A8MUA0 can act on the native protein depends on physical access: surface and secreted proteins are reachable by circulating antibodies, intracellular proteins usually are not.

Antibody reachability
Unknown
Secreted
No
Transmembrane segments
0
Mean surface accessibility (rSASA)
0.72

Protein domainsUniProt · Pfam · InterPro

Antibody and autoantibody relevanceSeroatlas analysis

Seroatlas reads A8MUA0 as an antibody target. Whether an autoantibody or antibody against A8MUA0 could matter depends on whether native A8MUA0 is physically reachable, whether the body needs it intact, and whether it acts in a disease-relevant tissue.

A8MUA0 is annotated as predominantly intracellular. Intracellular proteins are common autoantibody markers, becoming visible to the immune system after cell injury or altered processing, but are usually markers of disease rather than direct drivers.

Annotation status

The present source text does not explicitly label A8MUA0 as an autoantigen. Seroatlas presents hypothesis context only and does not manufacture a known-serology claim.

Canonical record: https://seroatlas.com/gene/A8MUA0. Study-independent annotations aggregated from UniProt, Human Protein Atlas, PubMed, IEDB, Pfam, InterPro, Gene Ontology, AlphaFold, gnomAD, DepMap, ClinVar, TCGA. Catalog release seroatlas-reviewed-human-uniprot-20260313.

Seroatlas is the reference for exploring autoantibody and antibody serology at the human-protein level: the autoreactome and human serome, multiplex serology (HuProt, HuScan, VirScan, PhIP-Seq).

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